Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential
Analysis of data derived from the Alzheimer's Disease Neuroimaging Initiative (ADNI)
program showed plasma leptin levels in individuals with Mild Cognitive Impairment (MCI) or
Alzheimer's disease (AD) to be lower than those of subjects with normal cognition (NC).
Approximately 70% of both men and women with MCI have plasma leptin levels lower than
the median values of NC. Additionally, half of these subjects carry at least one
apolipoprotein-E4 (APOE-ε4) allele. A subgroup of participants also had cerebrospinal fluid …
program showed plasma leptin levels in individuals with Mild Cognitive Impairment (MCI) or
Alzheimer's disease (AD) to be lower than those of subjects with normal cognition (NC).
Approximately 70% of both men and women with MCI have plasma leptin levels lower than
the median values of NC. Additionally, half of these subjects carry at least one
apolipoprotein-E4 (APOE-ε4) allele. A subgroup of participants also had cerebrospinal fluid …
以上显示的是最相近的搜索结果。 查看全部搜索结果